Difference between development of ovary and testis
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Difference between development of ovary and testis
Development of ovary
1.
intermediate mesoderm form urogenital ridge, a
longitudinal elevation at the dorsal body wall of fetus
2.
The coelomic epithelium and underlying mesoderm of
the urogenital ridge proliferate to form the gonada ridge
3.
The coelomic epithelium forms irregular primary
sex cords and incorporate primordial germ cells which migrate from the wall of
yolk sac
4.
The primary sex cord extends deep to medulla and dissociate
into irregular cell clusters which eventually degenerate and replace by
vascular stroma, the ovarian medulla.
5.
The surface epithelium of female gonad unlike that
of the male continues to proliferate
6.
In the 7th week of development it
produces second generation of cords, cortical cords, which penetrate underlying
mesenchyme but remain close to the surface do not extend into medulla.
7.
In the 3rd months, the cortical cords
get fragmented and form isolated cell cluster.
8.
Each cell cluster consists of a primordial germ
cell in the center surrounded by a layer of celomic epithelial cells
9.
The primordial germ cells form oogonia and
coelomic epithelial cells form follicular cells. The resulting structure is
called primordial follicles which remain confined in the cortex of the ovary
10.
A large number of primordial follicles are formed
during fetal life
11.
No new primordial follicles are formed after birth
12.
The further development of primordial follicles takes place after
puberty
13.
Tunica albuginea formed around the testis but in
case ovary tunica albuginea is not formed . the surface epithelium of ovary
flattens to form a single layer of cells , called germinal epithelium which is
continuous with peritoneum
14.
The connective tissue of ovary derived from
mesoderm
Development of testis
Development of testis
1.
Intermediate mesoderm
forms the urogenital ridge, a longitudinal elevation at the dorsal body wall of
the fetus.
The coelomic epithelium and underlying mesoderm of the urogenital ridge
protifelate to form the gonadal ridge.
The coelomic epithelium forms irregular primary sex cords and incorporative
primordial germ cells, which migrate from the wall of the yolk sac.
The primary sex
The development of the testis ord extends deep into the medulla to form
medullary cords, which lose their connection to the surface epithelium as the
thick tunica albuginea forms in between the medullary cord and coelomic
epithelium.
2. Near the
hilum medullary cord break up into network of tiny cell stands that form rete
testis
3. By the 4th
month of interuterine life medullary cord is continuous with rete testis
4. The
testis or medullary cord contain and primitive germ cells and sustentacular
cell of sertoli cell which derived from
the surface epithelium of genital ridge.
5. Sertoli
cell secrete mullarian inhibiting factor (MIF) which degenerate mullarian duct
6. Interstitial
cell of leydig derive from mesenchyme of genital ridge which derived from
intermediate mesoderm ,By the 8th week of gestation leydig cell
begin to produce testosterone which influence development of genital duct and
external genitalia
7. The
testis or medullary cord of testis remain solid cord until puberty , then it become
canalize and known seminiferous tubule, the canal of seminiferous tubules are
continuous with rete testis which inturn join with efferent ductile. The
efferent ductules and other excretory part of male genital system derived from
mesonephric or wolffian duct
|
Development of Testis |
Development of Ovary |
|
Formation of only one
generation of sex cords know as medullary cords which produce seminiferous
tubules and rete testis |
Formation of two generations
of sex cords a) 1st generation of sex cords like
medullary cords form stroma of ovarian medulla b) 2nd generation of sex cords
cortical cords form primordial ovarian follicles |
|
Formation of tunica albuginea
separating seminiferous tubules from surface epithelium |
No formation of tunica
albuginea The ovarian follicle are not
separated from surface epithelium |
|
Present of SRY gene develop
testis |
Absence of SRY gene develop
ovary |
|
Following genes are act
during development of testis : STY, TDF,SOX9,FGF9 |
Following genes are act
during development of ovary :
wnt4,SOX9,FOXL2 |
|
The production of
testosterone in the human fetus begins shortly after the testis
differentiates (around 8 weeks of gestation), and the maximum amount of
testosterone in the fetal testes is reached between 10 and 15 weeks of fetal
life. |
8th week of intrauterine
life. the ovaries are formed, they start to produce hormones such as estrogen
and progesterone, which are crucial for the development of the female
reproductive system and the overall growth and maturation of the fetus. |
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