Difference between somitomere and somite of paraxial mesoderm
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Difference between somitomere and somite
Somitomeres and Somites: Key Differences and Development
Both somitomeres and somites originate from the paraxial mesoderm and play crucial roles in the formation of the axial skeleton, muscles, and dermis.
1. Somitomeres
🔹 Definition: Somitomeres are loose masses of mesoderm that appear in a cranial-to-caudal sequence along the embryonic axis before forming somites.
🔹 Characteristics:
- First seen in the paraxial mesoderm during the third week of development.
- Less organized than somites.
- Found in the head and neck region (first 7 pairs do not form somites).
- Contribute to craniofacial muscles, pharyngeal arches, and extraocular muscles.
🔹 Fate:
- The first 7 pairs contribute to head and neck structures.
- Caudal somitomeres condense into somites in the occipital and trunk regions.
2. Somites
🔹 Definition: Somites are well-organized, paired blocks of mesoderm that develop from somitomeres in the occipital to sacral region.
🔹 Characteristics:
- Begin forming around day 20 in a cranial-to-caudal sequence.
- Total of 42–44 pairs of somites form, but some later regress.
- Highly organized compared to somitomeres.
🔹 Fate: Somites differentiate into three major components:
- Sclerotome → Forms vertebrae and ribs.
- Dermatome → Forms dermis of the skin.
- Myotome → Forms skeletal muscles of the body and limbs.
|
Somitomere |
Somite |
|
Loosely organized segmented collections of paraxial mesoderm in
the cranial region |
Epithelial balls of cells formed in segmented pairs along the
neural tube from paraxial mesoderm |
|
It form muscles and bones of the face and skull |
It forms vertebrae, muscles of the back and body wall and dermis
of skin |
|
It has no subdivision |
It has three subdivision dermatome myotome sclerotome |
|
It is situated cranially |
It is situated caudally |
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